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Intra-operative Multimodal Non-rigid Registration of the Liver for Navigated Tumor Ablation

Institution:
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Publisher:
Int Conf Med Image Comput Comput Assist Interv. MICCAI 2009
Publication Date:
Sep-2009
Citation:
Int Conf Med Image Comput Comput Assist Interv. 2009;12(Pt 1):837-844.
Keywords:
Non-Rigid Registration, CT guided liver ablation, liver tumor ablation, B-Spline registration, cryoablation
Appears in Collections:
SNR, SLICER, SPL
Generated Citation:
Elhawary H, Oguro S, Tuncali K, Morrison P, Shyn P, Tatli S, Silverman S, Hata N. Intra-operative Multimodal Non-rigid Registration of the Liver for Navigated Tumor Ablation. Int Conf Med Image Comput Comput Assist Interv. 2009;12(Pt 1):837-844.
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CT guided tumor ablation of the liver often suffers from a lack of visualization of the target tumor and surrounding critical structures. This information is available on pre-operative contrast enhanced MR images and a nonrigid registration technique is desirable. However while registration methods have been successfully tested retrospectively on patient data, very few have been incorporated into clinical procedures. A non-rigid registration technique has been evaluated, optimized and validated to be able to perform registration of the liver between MR to CT images, and between intra-operative CT images. The method requires pre-processing and segmentation of the liver, and presents an accuracy of approximately 2mm. A clinical feasibility study has been conducted in 5 liver ablation cases. The method helps clinicians enhance interventional planning, confirm ablation probe location with respect to the tumor, and in the case of cryotherapy, evaluate tumor coverage by the ice ball.

Additional Material
1 File (139.373kB)
Elhawary-MICCAI2009-fig2.jpg (139.373kB)